memyselfandi12345432
memyselfandi12345432 memyselfandi12345432
  • 08-07-2017
  • Biology
contestada

Why does the enzyme pepsin (present in the stamch) denature in the intestine?

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elizabethlily elizabethlily
  • 08-07-2017
 The enzyme denatures due to the alkaline environment of the intestine.
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budwilkins
budwilkins budwilkins
  • 08-07-2017
Correct, Pepsin denatures in the small intestine (duodenum) due to the higher pH (more basic or alkaline), and also the lack of HCl (neutralized by the base bicarbonate in the duodenum), which is a potent activator of pepsin in the stomach.
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