Mitosis do the sister chromatids separate and head towards opposite poles of the cell during anaphase.
During anaphase, sister chromatids (or homologous chromosomes for meiosis I), will separate and flow to contrary poles of the cell, pulled via way of means of microtubules. In nondisjunction, the separation fails to arise inflicting each sister chromatids or homologous chromosomes to be pulled to 1 pole of the cell.
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